Top 10 Best Marijuana Strains for Depression – Expert Reviews

Many people use marijuana to feel a sense of upliftment and inspiration to fight sadness and depression. Cannabis-related studies and user experiences show that proper intake of cannabis can stimulate mood by elevating enthusiasm. Read this article to understand how cannabis tackles symptoms of depression and explore the best marijuana strains for depression.

When we think of the best medical marijuana strain for depression, the ultimate stress-reliever that can jolt you with a boost of motivation is the Pineapple Haze strain; visit the official website to buy pure seeds.

What is Depression?

best cannabis strains for depression

Depression is a mood disorder that affects how individuals feel, think, and act. It causes a feeling of sadness and lack of interest in activities that they previously enjoyed. It could happen to anybody at any age, and there are a couple of things that can increase the risk of depression, such as:

  • tensions
  • regular smoking
  • hardship in life
  • personal or medical problems
  • financial, professional, or social problems

Can Marijuana Treat Depression?

Depression is a complicated disorder that impacts every person differently. On the other hand, weed is a mind-boggling plant that delivers distinct effects by varying degrees to different individuals. These complexities have made it difficult for researchers to establish a firm connection between marijuana and mood disorders.

Some studies and many user-reported comments reveal that cannabis could temporarily ease depressive symptoms. Many proofs from cannabis users show positive results in managing depression. However, other studies warned that long-term cannabis use could lead to other psychological issues.

The Role of THC, CBD, and Terpenes to Fight Depression

Tetrahydrocannabinol (THC) is the essential psychoactive cannabinoid responsible for producing the euphoric “high” usually associated with weed. Numerous individuals who use marijuana to alleviate their depression prefer high THC marijuana strains. THC cannabinoid spurs the release of serotonin and dopamine, which are neurotransmitters associated with sensations of pleasure.

Like antidepressant medicines, THC creates feelings of happiness and cerebral high that temporarily prevent depression. Some THC-heavy best strains like Granddaddy Purple and Northern Lights are also high in limonene, linalool, myrcene, pinene, and other terpenes that may help your mind and body relax.

However, it’s important to realize that heavy usage can dull the dopamine system, worsening overall mood. For this reason, some doctors don’t prescribe high THC strains to anxiety and depression sufferers.

Cannabidiol (CBD) is well-known as a non-psychoactive cannabinoid that does not cause a euphoric “high.” Study shows that CBD can be used to lessen symptoms of anxiety and depression. CBD carries calming and anti-anxiety characteristics and can reduce depression. Many people opt for CBD treatment to relieve anxiety, fear, and lack of sleep. If you crave high CBD strains for medical benefits, it could relieve the symptoms of depression, especially for people dealing with cognitive impairment, anxiety, and public speaking.

Terpenes are other secret weapons to fight depression. Look for strains rich in Caryophyllene, Linalool, and Limonene that can help ease depression and anxiety.

Best Medical Marijuana Strains for Depression

bob marley quote about marijuana

There are some best medical cannabis strains for depression that you can choose to have peace of mind and body. Below are the best strains that may help alleviate symptoms of severe mental conditions.

#1 – Jack Herer

Jack Herer

Exceptionally high in Limonene and other terpenes, it’s a hybrid strain between a secret Sativa Haze, Northern Lights, and Shiva Skunk. It comprises 10% Indica and 90% Sativa. It’s a Sativa-dominant strain that got its name after a famous cannabis activist ‘Jack Herer’ who is also an author of the best-selling book ‘The Emperor Wears No Clothes.’

This cannabis is one of the great strains to use in the daytime. Moreover, it’s an uplifting strain instant mood booster. Jack Herer marijuana strain generates pleasant cerebral buzz, focus, strength, and creativity. Besides, it promotes laughter, chattiness, and active social behavior. Moreover, it also relieves stress, alleviates depression, and stimulates appetite. With unique flavors and terpenes profile, it’s one of the best medical cannabis strains.

#2 – Harlequin

Harlequin strain

Harlequin is a hybrid strain between Swiss Sativa, Thai, Colombian Gold, and Nepali Indica. Harlequin hybrid strain has 80% Sativa and 20% Indica. Furthermore, it’s popular cannabis among users for treating various disorders. The strain has a 1:1 THC to CBD balance, making it suitable for medicinal applications.

You’ll get to enjoy the smooth smell and unique flavor profile. Harlequin is one of the most suitable strains for morning and daytime use. Besides, the Harlequin marijuana strain is known to induce lucid high with minimal psychotropic effects. It could help improve mood, boosts energy, and increases focus. It may help relieve depression, alleviates cramps, and provides effective pain relief, making it one of the finest strains in the medicinal cannabis community.

#3 – XJ-13


XJ-13 cannabis strain is a cross between G-13 and Jack Herer cannabis strains. XJ-13 incorporates 50% Sativa and 50% Indica genetics. Moreover, it also comes with 22% THC content and holds β-Pinene and α-Pinene. On the flavor profile, you get to enjoy sweet and spicy tastes, with notes of pine and citrus.

Experience this well-known strain that can often manage depression, stress, pain, and anxiety, making it ideal for day and evening use. Apart from that, XJ-13 cannabis strain renders effects of cerebral buzz that kicks in quickly, lifting you with intensity and a great body buzz that could also make you talkative and creative.

#4 – Pineapple Haze

Pineapple Haze strain

High in myrcene, beta-caryophyllene, alpha-Pinene, and other terpenes, Pineapple Haze holds 30% Indica and  70% Sativa genetics. It’s known to cross-breed from Pineapple Hybrid and Haze Sativa due to its pineapple taste and smell. However, some say that it was bred from Hawaiian and Trainwreck strains. It’s a Sativa-dominant hybrid strain that holds high THC content of up to 19%.

Experience this ultimate day strain that often induces different positive feelings, including uplifting euphoria, creativity, and relaxation. Besides, Pineapple Haze can effectively manage many physical conditions like lack of appetite, nausea, fatigue, headaches, migraines, and chronic pains. Other than that, it can also be used to treat depression, stress, PTSD, anxiety, insomnia, nausea, ADD/ADHD, and PMS.

#5 – Cannatonic

Cannatonic strain

Cannatonic is a hybrid strain made up of MK Ultra and G-13 Haze. High in myrcene, beta-caryophyllene, pinene, and limonene terpenes, the Cannatonic marijuana strain is known as an exotic marijuana hybrid. Moreover, it has about 1:1 THC to CBD ratio that can help reduce pain and managing side effects of numerous health disorders.

Apart from that, Cannatonic has citrus, herbal, and pine aroma. It’s suitable for evening and nighttime use, be it medical or recreational use. Cannatonic marijuana strain induces mellow body buzz and promotes uplifting euphoria. Furthermore, it uplifts mood, lightens depressive thoughts, and stimulates appetite.

Final Verdict

Depression is a severe mental condition, and marijuana is a mind-boggling plant to relieve it. For that reason, you may need to try several strains until you settle on the right combination. More on that note, start with a low dose and, if necessary, slowly increase it under the guidance of a medical marijuana doctor to prevent any adverse effects. Seeking professional help is always a better way to understand the right strain, dosage, and ingestion method.

Above-reviewed strains could lessen depressive thoughts by boosting mood and energy. We hope this medical marijuana guide for depression will help you choose the right cannabis if you strive to reduce depression and anxiety.

Let us bid adieu by quoting famous words by Buddha: “If we could see the miracle of a single flower clearly, our whole life would change.

Good Luck & Happy Healing!

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