Top 10 World’s Best Marijuana Strains to Try At Least Once

As time passed, individuals started experimenting with landraces, crossbreeding different combinations of male plants and female plants to deliver new strains. However, you may ask, what are the best marijuana strains to try at least once? So, let’s dive deep into the topic and also explore some of the world’s best cannabis strains that you need to try at least once in your lifetime.

While exploring the best cannabis strains to try at least once, the first strain that comes to our mind is the Master Kush cannabis strain; visit the official website to buy high-quality marijuana seeds.

Most dispensaries have a vast assortment of strains on display. Choosing which strains to try to smoke can be overwhelming. This post will sort most of your cannabis-related queries, their properties, and strains worth trying. 

What are marijuana strains?

First, let’s jump into a touch of cannabis history. Cannabis has originated in ancient Asia, but after some time, the plant went the world over, where it was planted and cultivated. After some time, these plants are accustomed to their new climate, resulting in changes to their physical and substance characteristics. These plants got known as landrace strains. 

As time passed, individuals started experimenting with these landraces, crossbreeding different combinations of male plants and female plants to create new strains. This experimentation gave birth to the ever-growing assortment of cannabis plants in existence today. We call the varieties strains. 

Historically, cannabis has been cultivated mostly underground because of disallowance during the turn of the century. 

What makes cannabis strains one of a kind?

There is an assortment of elements that make up a strain’s one of a kind profile: 

Cannabinoid content

The cannabis plant holds a host of cannabinoids, substance compounds that interact with the body’s endocannabinoid system to create various effects. A strain’s cannabinoid profile or the convergence of cannabinoids like THC and CBD is a crucial differentiating characteristic. For instance, strains with high THC and almost no CBD are more intoxicating, while strains with a 2:1 CBD to THC proportion can be more loosening and produce less of an intense high. 

Terpene content

Terpenes are fragments in the cannabis plant that render flavor and smell and help support cannabinoids and different cannabis molecules in creating effects in both the body and the mind. The cannabis produces more than 200 terpenes, and specific strains will have diverse terpene profiles and concentrations. Thus, strains can have different aromas, flavors, and effects. 

Ecological variables

Ecological variables during cultivation, similar to the soil nutrients, can influence both the cannabinoid profile and terpene, so the same cannabis in different environments could be another strain. 

Choosing Indica, Sativa, and Hybrid Strains

A strain’s organization as Indica, Sativa, or hybrid isn’t about particular effects. It’s about the physical attributes and structure of the plant. 

Another set of terms you’ve likely heard regarding cannabis strains is Indica, Sativa, and hybrid. But chances are, what you’ve found out about them presumably isn’t precise. 

Most individuals think that Indica, Sativa, and hybrid can describe a specific strain’s effects. Sativa produces an uplifting, cerebral high; Indica strains leave users more relaxed, mellow, and sleepy; and hybrids have some combination of the two. 

Indeed, a strain’s classification as Indica, Sativa, or hybrid isn’t actually about specific effects. It’s about the plant’s physical characteristics and structure, which can be useful for growers, but not so much for consumers. 

How to choose which cannabis strain to try

There are a couple of standards you’ll need to consider when choosing a strain: 

Flavor and smell

A strain’s terpene profile can create subtle or intense flavors and aromas. As per your preferences, you can pick a weed that provides that flavor and fragrance at the intensity that suits you. 

Desired effects

Everyone responds to cannabis differently, and there’s no assurance that a strain will deliver a specific impact. However, you can try strains with a cannabinoid and terpene profile that will probably create your desired effect. For instance, if you need to experience intoxicating effects, it would make sense to go with something with a higher THC content. If you are looking for an unwinding background, you might try a strain containing linalool; a terpene reported to have stress-relieving properties. 


Depending on the grouping of cannabinoids, primarily THC, some strains are more intense than others, and the degree of energy you’re looking for can assist you with deciding which strains to try. Try something more potent for an elevated high. Do you crave for a less sharp one? Go with something that carries a moderate THC level. 

Growing method

Some individuals have a preference for weed that is grown in or outdoors. If you’re one of those individuals, you’ll need to try strains that align with your personal preference. 

Potential medical benefits

Depending on a strain’s cannabinoid proportion or terpene profile, it could have various possible medicinal qualities. If you’re thinking about using cannabis to manage a medical condition, converse with a medical professional to determine which strains might be useful. 


There are strains for every budget, from wallet-accommodating to high-end. If you have a specific cost in mind, that can play into which cannabis strains you choose to try. 

Cannabinoids and terpenes for medical marijuana use

Concentrations of each type of cannabinoid range broadly from strain to strain and plant to plant.

The first classified and best-known cannabinoid is THC (delta-9-tetrahydrocannabinol). It has the most significant psychoactive effect of the cannabinoids. The proportion of THC to different cannabinoids varies from strain to strain. While THC has focused on breeding and research because of its various psychoactive and healing effects, non-psychoactive cannabinoids have physiologic outcomes that can be remedial. 

Cannabidiol (CBD) relieves convulsions, inflammation, anxiety, and nausea—a significant number of the same helpful qualities as THC but without psychoactive effects. It is the primary cannabinoid in low-THC cannabis strains, and present-day breeders have been developing strains with more significant CBD content for medical use. 

Tetrahydrocannabivarin (THCV) is exhibiting promise for type-2 diabetes and related metabolic disorders. 

Cannabigerol (CBG) has soothing impacts and antimicrobial attributes, as well as decreases intraocular pressure. 

Cannabichromene (CBC) promotes the analgesic effects (pain help) of THC and has sedative (calming) effects. 

Cannabinol (CBN) is somewhat psychoactive, decreases intraocular pressure and seizure event. 

Notwithstanding cannabinoids, different cannabis plant molecules are biologically active. A couple of other molecules known to have health effects are flavonoids and terpenes or terpenoids (the strain’s flavor and smell). The glandular trichomes secrete cannabinoids, terpenoids, and compounds discovered most densely on female plants’ floral leaves and flowers. 

Effects of Sativa, Indica, and Hybrid Marijuana on Health

Different individuals have different experiences. One individual may feel stress help, while another feels over-stimulated and stressed, while another feels energized and on-task. Numerous factors impact the effect: 

  • A strain of cannabis
  • Method of consumption 
  • Dosage
  • Climate/setting 
  • Experience and history of cannabis use 
  • Biochemistry 
  • Mindset
  • Diet 

What are the different types of cannabis?

Though cannabis is biologically labeled as the single species Cannabis Sativa, there are three distinct plant classes: Indica, Sativa, and Ruderalis, though the last one is uncommon. There are also hybrids, which are crosses among Sativa and Indica species. Cannabis for making fiber is hemp and has just small amounts of the psychoactive cannabinoid, THC, usually less than 1%. 

In general, below are some characteristics of Sativa, Indica, and Hybrid strains. 

Sativa Strains

The essential effects are on thoughts and feelings. Sativas will, in general, deliver stimulating sensations, and many prefer it for daytime use. 

What are the medical benefits of cannabis Sativa?

  • Stimulating/energizing 
  • Increases sense of well-being, focus, innovativeness 
  • Reduces depression, elevates mood. 
  • Relieves headaches/migraines/nausea 
  • Increases appetite 

What are the side effects of cannabis Indica? 

  • Increased anxiety
  • Increased neurosis feelings 

Indica Strains

The essential effects are on the body. Indicas will, in general, deliver sedated, and many favor it for nighttime use. 

What are the therapeutic benefits of cannabis Indica?

  • Provides relaxation
  • Relaxes muscles
  • Reduces stress 
  • Reduces pain and inflammation
  • Alleviate headaches and migraines 
  • Better sleep
  • Reduces anxiety 
  • Reduces nausea
  • Appetite booster
  • Reduces intraocular pressure 
  • Reduces seizure

What are the side effects of cannabis Indica?

  • Lazy
  • Sleepy
  • Unclear thinking

Hybrid Strains

Strains bred from hybridizing two or more races, with typically one dominant. For instance, a Sativa-dominant cross may help stimulate appetite and relax muscle spasms. Hybrids work well to battle nausea and increase appetite.

What is the importance of lab-tested cannabis strains?

Not just does lab testing let you recognize what’s in your strain, but it also enables you to realize that the cannabis you’re consuming is safe. Various characteristics make up individual strains. To effectively choose whether you need to try a strain, you have to comprehend what those characteristics are, and that is where lab testing comes in. 

Any cannabis you purchase in a legal dispensary is expected to undergo rigorous laboratory testing to ascertain both the cannabinoid and terpene profiles. It also examines to make sure the bud doesn’t contain destructive pesticides, fungicides, or different chemicals, leading to health issues. 

Not just does lab testing let you realize what’s in your strain, which can assist you with deciding which strains to try, but it also enables you to recognize that the cannabis you’re consuming is safe, regardless of what strain you choose. 

How should I choose a strain that is right for me?

We can use the cannabis plant to make papers, clothes, ropes, and building materials. On the other hand, leaves, flowers, and roots can be used for medicinal purposes. Besides, We can use seeds for food and oil. 

You can consume cannabis leaves and flowers in several manners: dried flower buds or different types of concentrated, loose, or crushed resin extracted from the buds or leaves.

When developed, trichomes spread the plant’s leaves and flowers. Trichomes are tiny glands of resinous oil containing cannabinoids and terpenes that give physical and psychoactive effects. 

When it comes to picking a perfect weed strain, there’s nobody size-fits-all approach. The strains that others love might fall short for you (and vice versa). 

But since you know the defining characteristics of each strain and how to assess them, you have the information you have to explore what’s available and choose the right strains for you. 

Top 10 Popular Marijuana Strains in 2021

#1 – Blackberry Kush

blackberry kush cannabis strain

Blackberry Kush is a potent Indica-dominant strain. This intense bud, with its unique aroma, is a favorite strain among savvy smokers. Moreover, both recreational users and medical users enjoy it for its euphoric impacts. And, just like Blackberry Kush seeds suggests, this is one sweet-smelling strain. 

With Blackberry Kush, your tongue will experience a diesel-like, earthy flavor, cut with an exceptionally intense presence of sweet blueberry. With every toke, your palette feels the taste of berries. And, the sugary sensation will remain in your mouth for a long time. 

This strain gets you a more potent euphoria than the average cannabis delivers. It is because it contains 16% to 20% THC. Prepare yourself for a quiet ride that will help calm your stress and manage your chronic pain. 

#2 – Dwarf Low Flyer

Dwarf Low Flyer

Bantam Low Flyer autoflower marijuana is easy to moderate grow and can flourish in indoor and outdoor growing areas. Low Flyer is undoubtedly a sure hit with 20% Sativa, 70% Indica, and 10% ruderalis. Moreover, it’s a cross between Early Girl, Low Rider, and Ruderalis. Just like a large number of the best strains available nowadays, this one originated from Spain. 

At 10.85%, this beautiful plant’s THC content is nowhere as high as some other strains, but that’s what sets it apart. Low Flyer delivers a sweet and smooth natural kind of buzz. It is pure fun and relaxation, with no extraordinary psychedelic or couch-locking effects. 

It is the perfect smoke for those times you need to relax and then go back to whatever you were doing. A good alternative for beginner smokers and veterans who need something moderately gentle for a change. 

#3 – Gold Leaf

Gold Leaf strain

It is a strain that ILGM’s Robert Bergman cultivated himself and loves! He bred it, so it is easy to develop, grow into tall, bud covered plants, have an average flowering time, and produce too high yields. 

The Gold Leaf Strain has a unique scent. It is not typical for anything else available. When you first light a joint, you will get an earthy-sweet scent, transitioning to a fresh piney smell. It is an Indica-dominant weed and highlights a one of a kind and intense fragrance you will immediately come to adore. 

If you like noticing an immediate response, you will adore the close instant lift in the mood. Right away, you’ll observe an uplifted, happy, and relaxed state of mind. From there, you’ll transition rapidly into euphoria-driven imagination that can bring you through the day. 

#4 – Badazz Rolex Feminized

Badazz Rolex strain

Badazz Rolex renders a sedating high that gives you intense body sensations. This hybrid offers a fantastic mix of spice and sweetness that also boasts of a great aftertaste. It is also a medicinal strain fit for reducing pain, stress, tension, anxiety, muscle pains, etc. 

The surpassing thing about the Badazz Rolex is that it begins with a balanced euphoria. It effuses a damp fragrance having subtle notes of fruits and earth. Besides, it perfectly blends sweetness and exceptional spiciness. Moreover, highlights of a fruity flavor will leave you in such a pleasant aftertaste. 

It is a dominant hybrid that has been impressing individuals because of its delicious flavor. This remarkable flavor is a mixture of piney and skunky zest with cheesy notes. This Bad Azz Kush and Rolex OG Kush mixture are famous for energizing euphoria and relaxing buzz. It is perfect when it comes to easing muscle tension and stress. It can leave you enjoying more of its herbal scent, flavor, piney, and spicy. 

#5 – Master Kush


This almost pure Indica strain is a door to heaven on the marijuana market. It’s because of its public shoutouts from well-known celebrities, such as rapper Snoop Dogg. 

With a composition of 95% Indica and 5% Sativa, this cross strain has won two Cannabis Cup awards. It combines the world-renowned Hindu Kush with Skunk #1 or bred with two different Hindu Kush varieties. 

The Indica-dominant Master Kush has an intense THC level of up to 24%. It gives it the capacity to induce a euphoria that calms you while slowing down your body. 

If you are a working person who experiences a ton of stress, you will adore its relaxing effects. You’ll experience help from the stress that lasts for hours, allowing you to continue being productive throughout the day. At that point, at night, as your buzz comes down, you’ll be completely relaxed and prepared for a sleep that lasts the whole night. 

#6 – Original Skunk

Original Skunk strain

This stinky plant announces its full, intense presence from miles away. This strain has THC levels reaching over 15%. Although this level is not as high as those of several strains, Original Skunk regular seeds are favored and disparaged by users and growers because of its novel characteristics and unique effects. 

Original Skunk does not cause excessively psychedelic effects. The high is mainly a good body buzz, quickly gluing you to the couch while keeping your muscles and limbs soothed and quiet. Original Skunk also produces effects that may profit medical marijuana patients. Anybody suffering from exhaustion, body pain, and similar problems can benefit from this strain. 

#7 – Gelato

Gelato Strain Review

Are you looking for an easy smoke that hits hard every time? You are going to cherish Gelato! Even experienced smokers with high tolerance start to feel it after a couple of moments. 

This strain is a pure organic flavor from all angles. The aroma is sudden and reminds us of Girl Scout Cookies and Thin Mint. When you lit it, you’ll get notes of sugar, sweetness, and an undernote intensely loaded up with cream and pine. 

Gelato has great THC content and produces immediate and uplifting happiness – at an extraordinary level. It’s fair toward the back by a piercing physical relaxation to give a little equalization to the overall experience. A unique element of this weed is that although it has amazingly high THC, it’s also fabulous for a daytime smoke. Rest assured that your mind will remain fresh and your thoughts clear. 

#8 – Black Water Purple OG Cheese

Black Water Purple OG Cheese

The Black Water Purple OG Cheese is a 3-way hybrid strain that has been a brilliant evening smoke. Aside from its medicinal prowess, she can also be suitable for recreational use. Its viability in the two purposes is because of an average THC content that ranges from 15-18%. 

It is the ideal nighttime smoke that will assist you with getting that well-deserved sleep. It also has that novel cheddar and berry taste that you will recall. Soon after its berry and cheddar taste touches your sense of taste, a cerebral buzz will immediately hit your mind and take you to the “clouds.” 

Also, you will experience a quiet physical sensation that touches your body. You may struggle to move when you feel this, but the case is different when you take Black Water Purple OG Cheese at a low dosage. 

#9 – Matanuska Thunder


Matanuska Thunders’s fragrance and taste will make your mouth water with its rich chocolate flavor. Delicious to smoke, this Indica-dominant strain renders creeper notes, making it ideal for evening and relaxation use. 

It is as snowy as the Alaskan hills, with THC levels of 18-22%. It’s an intense Indica strain that is short and bushy and covered in snowy crystals. The stone is a genuine creeper hitting profoundly over a more extended period. 

The sensation radiates from your toes to head like you are descending into a smoke shower. It starts to ease muscular pains and promotes a general feeling of well-being and leisure. With greater use, it becomes more opiate and will induce profound restful sleep. 

#10 – Lowryder Autoflower

Lowryder Autoflower

Lowryder seeds are easy to grow because of their Ruderalis genetics. Lowryder autoflower seeds are small in size. It is one of the first autoflowering strains of marijuana. Although small, lowrider has noticeable cerebral effects. The onset is slow yet satisfying. 

Lowryder comes on slow, so tolerance is essential if it’s your first time. When it hits, it delivers healthy relaxation that might take care of you. The medium levels of THC take their time, providing a dose of happiness and inventive thoughts. However, keep some paper around to record those thoughts because you will most likely be too relaxed to act on them. 

Lowryder has a distinctly earthy and aromatic fragrance. In terms of flavor, it has a combination of citrus and sweet, likely from its Sativa genetics. The mood-enhancing quality of this strain can help with both pain and negative thoughts.

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