Top 10 Best Hybrid Strains 2022 – Reviews & Buyer’s Guide

Which is the best hybrid weed strain in the world?

If you ask me, White Widow is the one!

Go ahead and get yours, right now.

If you’re bemused on choosing among the energetic head-high of Sativa and the sensationally soothing sensations of Indica, well, you can always settle for the third one: Hybrid strains.

They are crossbred from Indica and Sativa strains to various degrees to deliver a refreshing combo of effects and flavors. Explore this guide and look into the top 10 best hybrid strains to try in 2022.

Are all hybrid strains the same?

Not all hybrids are the same; in fact, the plant structure, yield, potency, effect, aroma, and taste greatly vary among different hybrids. As expert cannabis geneticists come up with groundbreaking fusions, the resulting hybrid weeds carry significant heterogeneity in different varieties.

As popular Sativa and Indica landrace are truly transcending on their own, many top-shelf hybrid cannabis strains can tempt you beyond your wildest imagination. 

That’s the reason behind hybrids becoming more and more popular!

Uncovering the properties and advantages of these hybrid strains can help you find a better weed tailored to your recreational or medical purpose.

Buy Top 10 Best Hybrid Strains

Are you looking to whiff some bongs and have fun with your buddies? Do you crave to be creative and bring a genius out of you? Or do you just need to drift in relaxation and forget your pain? Whatever you seek, these top 10 best hybrid weed strains are sure to fascinate you in your needs. Check the reviews of each hybrid strain below!

#1 – White Widow | All-Time Best Hybrid Strain

White Widow strain ILGM

White Widow Strain Information 🌱

  • Seedbank: ILGM
  • Variety: 60% Indica + 40% Sativa
  • Sex: Feminized
  • Genetics: South Indian Indica + South American Sativa
  • THC: Up to 19%
  • CBD: Insignificant amounts
  • Growing Difficulty: Easy
  • Climate: Indoors, Temperate, Mediterranean, Steppe
  • Flowering Time: 9 weeks
  • Yields: 18oz/sqft
  • Flavors: Earthy, Woody, Pungent, Spicy, Herbal
  • Effects: Euphoric, Happy, Relaxed, Creative, Uplifted, Euphoric
  • Medical Benefits: Fatigue, Stress, Aches

If you want to have shiny and milky trichomes on resinous buds, consider growing this marijuana strain. It’s a splendid parent of many famous and top-rated hybrid cannabis strains. This Indica-dominant hybrid is easy to grow marijuana, even for first-time growers.

From any local dispensary in the United States to Amsterdam’s coffee shops, White Widow is highly demanded among global recreational users for its reliable high. This variety is not forcefully potent, so you will enjoy a well-balanced high and stay productive, making it ideal for first-time consumers, occasional bongers, and hardcore stoners.

Great! I’m going to order this weed frequently; what about you?

White Widow was awarded a High Times Cannabis Cup in 1995. Not only that, it won 10 various awards from 1995 to 2006 for being the best strain in different categories. Overall, it’s one of the top hybrid strains.

Get White Widow at the lowest price

#2 – Gorilla Glue | Best High THC Hybrid

Gorilla Glue MSNL

Gorilla Glue Strain Information 🌱

  • Seedbank: MSNL
  • Variety: 50% Indica + 50% Sativa
  • Sex: Feminized
  • Genetics: Chem’s Sister + Chocolate Diesel + Sour Dubble
  • THC: Over 25%
  • CBD: below 1% 
  • Growing Difficulty: Easy
  • Climate: Indoors, Outdoors
  • Flowering Time: 7-9 weeks
  • Yields: Over 600 g/m²
  • Flavors: Earthy, Pepper, Pine, Sour, Tangy, Coffee-like bitterness
  • Effects: Energy, Euphoric, Uplifted
  • Medical Benefits: Stress, Depression, Muscle Spasms, Mood Swings, Insomnia

Perfectly balanced (50/50 Indica/Sativa) Gorilla Glue hybrid strain is potent, in fact, the best high THC cannabis out there. Above 25% THC levels are enough to boost your dopamine production. Just one puff is enough to lure you into the tongue-tingling zest of strong coffee, chocolate, and rain-showered soil.

True to its name, it produces sticky, dense, and resin-rich buds that contribute mesmerizing skunky, earthy, and sour scents. Along with all the medicinal purposes (as charted above), many users make it a home for getting the utmost relaxation from severe pain.

It’s not surprising to see that Gorilla Glue won the Los Angeles 2014 High Times Cannabis Cup. It’s a high-yielding and fast-growing strain. Use Gorilla Glue at night and float into a blissful dreamland. However, go slow with this strain as the high could be too sharp to handle. 

Get Gorilla Glue at the lowest price

#3 – AK-47 | Amazing Autoflower Hybrid

AK-47 strain ILGM

AK-47 Strain Information 🌱

  • Seedbank: ILGM
  • Variety: 65% Sativa + 35% Indica
  • Sex: Feminized
  • Genetics: Mexican Sativa + Thai Sativa + Colombian Sativa + Afghani Indica
  • THC: Up to 20%
  • CBD: <1%
  • Growing Difficulty: Easy
  • Climate: Indoors, Mediterranean
  • Flowering Time: 8 weeks
  • Yields: 110-170 g/sq.ft
  • Flavors: Sweet, Earthy, Floral, Spicy, Herbal, Skunk, Woody, Pine
  • Effects: Euphoric, Happy, Relaxed, Mentally Alert, Creative
  • Medical Benefits: Stress, Depression, Eating Disorder, Nausea

A special blend of exceptional genetics in the Sativa hybrid strains category! The roots of AK-47 go back to the 70s, making it an evergreen Sativa-dominant weed. Contrary to the Russian rifle, this Ak-47 is actually a calming and gentle weed. 

Do you listen to music or craft an art? You might go to a gym, yoga, or party at times, right? Very well! Next time, do one thing, have some AK-47 before any occasion, and watch yourself hop in a brilliant state of euphoria. 

This Sativa-dominant hybrid gets ready to be harvested in just 56 days, and you can expect 6-8 oz of buds per square meter. The sweet aroma and rich undertones that transpire from buds can certainly mellow any bitterness on your palate upon smoking.

Whether it’s Toronto Expo in 2010, Jamaican Cup, or High Times Cannabis Cup, Ak-47 has won several awards, reflecting its status and excellence.

Get AK-47 at the lowest price

#4 – Girl Scout Cookies | Multiple Award-Winning Hybrid

 Girls Scout Cookies (GSC) MSNL

Girl Scout Cookies Strain Information 🌱

  • Seedbank: MSNL
  • Variety: 60% Indica + 40% Sativa
  • Sex: Feminized
  • Genetics: OG Kush + Durban Poison
  • THC: 20-24%
  • CBD: Below 1%
  • Growing Difficulty: Moderate
  • Climate: Indoors, outdoors
  • Flowering Time: 8-10 weeks
  • Yields: 400-500 g/m²
  • Flavors: Cookies, Earthy, Spicy, Cinnamon, Nutmeg
  • Effects: Intense relaxation, Cerebral rush, Couch lock
  • Medical Benefits: Chronic Pain, Inflammation, Muscle tension, Cramps

This little lady has richly earned its name and fame among worldwide cannabis users, and for genuinely good reasons. If you’re a stoner, you must be well aware of the Girl Scout Cookies. I have tried bonging GSC many times, and I’m sure you did too.

With nearly 25% THC levels, it chills you out immensely. The soothing sensations of Indica and accelerating high of Sativa genetics will grip you so tight that you will realize what the best of both worlds is! Beginners might want to make themselves glued to their sofa. Many users consume GSC for treating chronic pain and getting mental relaxation.

Upon flowering, GSC offers a luscious and enticing fragrance that can feel from worlds away. With such desirable qualities, who wouldn’t want to enjoy a blunt of Girl Scout Cookies! Go ahead and get this tremendous higher-THC strain today. 

Get Girl Scout Cookies at the lowest price

#5 – OG Kush | Original Gangster of Kush

OG Kush - best hybrid strains

OG Kush Strain Information 🌱

  • Seedbank: Crop King Seeds
  • Variety: 75% Indica + 25% Sativa
  • Sex: Feminized
  • Genetics: Hindu Kush x Chemdawg
  • THC: 24%
  • CBD: 0.7%
  • Growing Difficulty: Easy
  • Climate: Mediterranean, Temperate, Continental
  • Flowering Time: 8-10 weeks
  • Yields: 400-500 g/m²
  • Flavors: Lemon, Spicy, Earthy, Pine, Woody
  • Effects: Euphoric, Relaxing, Extreme cerebral high, Cottonmouth, Dry eyes, Socializing
  • Medical Benefits: Chronic Pain, Migraine, Stress, Depression, Anxiety, Insomnia, PTSD, Appetite Boost, Nausea

OG Kush is a highly demanded, old-school classic strain being consumed widely in many legal states. If you plan to grow a fantastic indoor strain, you should seriously consider growing OG Kush. From celebrities to rappers, OG Kush had amazed everyone when it first emerged in Los Angeles in the early 90s.

OG Kush has contributed immensely to developing modern exotic hybrid strains. In fact, it’s one of the essential founding ancestors of many Kush phenotypes. Characteristics of Kush lineage are not to be taken lightly, especially with this original hard-hitter. You can even find new exotic strains 2022!

It’s a body-numbing nighttime strain that can sweep away any negativity you might have. You might feel stoned for hours if you whiff a high dose. Newcomers need to go slow and steady! Overall, it leaves consumers happy with a mind-boggling experience.

FYI: An actual meaning of OG is unknown; many theories assume different stories to propose OG as— Original Grower, Over Grown, Original Gangster, Ocean Grown, and Original Kush.

Get OG Kush at the lowest price

#6 – Wedding Cake | Modern & Delicious Hybrid

Wedding Cake strain

Wedding Cake Strain Information 🌱

  • Seedbank: ILGM
  • Variety: 70% Indica + 30% Sativa
  • Sex: Feminized
  • Genetics: Cherry Pie + Girl Scout Cookies
  • THC: Up to 17%
  • CBD: Very low
  • Growing Difficulty: Easy
  • Climate: Indoors, Continental
  • Flowering Time: 9-10 weeks
  • Yields: 500-550 g/m²
  • Flavors: Ginger, Sweet, Vanilla, Earthy
  • Effects: Relaxing, Energizing
  • Medical Benefits: Anxiety, Headaches, Stress, Depression, Muscle Cramps, Lack of Appetite

Are you looking to grow a strain that’s easy to cultivate and delivers instant chills? Try growing Wedding Cake in your garden, and I’m sure you can’t go wrong with it.

Crossed between GSC and Cherry Pie, hybrid strain Wedding Cake is also called Pink Cookies. It’s one of that rebellious strains that sustains extreme environmental changes to resist bacteria, pests, insects, mildew, diseases, and mold. It will get you a wholesome quantity of flowers in just 9-10 weeks.

The light smell will not bother you if you want to use it discreetly. It won’t induce couch-lock; instead, you can stay relaxed and enjoy its uplifting effects. I have seen a great many people admiring Wedding Cake weed. And, you too will be a fan of this exotic hybrid once you smoke a Wedding Cake joint.

Get Wedding Cake at the lowest price

#7 – Chemdawg | Fast Flowering & Potent High Pot

chemdawg cannabis strain

Chemdawg Strain Information 🌱

  • Seedbank: ILGM
  • Variety: 80% Indica + 20% Sativa
  • Sex: Feminized
  • Genetics: [Thai Sativa + Nepalese Sativa] or [OG Kush + Sour Diesel] (assumption)
  • THC: Up to 25%
  • CBD: 0.01% to 0.1%
  • Growing Difficulty: Moderate
  • Climate: Indoors, Mediterranean, Steppe
  • Flowering Time: 8 weeks
  • Yields: 400-480 g/m²
  • Flavors: Diesel, Pungent
  • Effects: Cerebral high, Balanced head high, Giggles, Relaxation, Uplifting, Munchies
  • Medical Benefits: Stress, Negativity, Pain, Anxiety, Lack of sleep

Chemdawg (or Chemdog) is a highly potent strain that has been a center of attraction for tangled opinions as the mystery of its parent genetics is still uncovered. But as they say, who cares about history when you get the best out of it. 

It can be grown indoors. Grow some Chemdawg plants and collect 400-480 grams worth of buds per square meter upon flowering. However, this plant needs protection from mold and pests. The moderate difficulty level suggests that growing Chemdog requires some experience to yield healthy THC-rich buds.

When it comes to effects, it’s crystal clear to foster a powerful euphoric high with just a few hits. The pungent diesel and chemical-like flavor will engulf your mouth as long as you stay stoned. Another exciting thing about Chemdawg is that it can prompt uncontrollable giggles! Do not consume in large doses to avoid mild headaches and paranoia. 

Get Chemdaw at the lowest price

#8 – Jack Herer | Best Sativa Dominant Hybrid in America

Jack Herer strain ILGM

Jack Herer Strain Information 🌱

  • Seedbank: ILGM
  • Variety: 60% Sativa + 40% Indica
  • Sex: Feminized
  • Genetics: Haze Sativa x (Northern Lights #5 x Shiva Skunk) Indica
  • THC: Up to 20%
  • CBD: Low
  • Growing Difficulty: Easy
  • Climate: Indoors, Mold Resistant, Mediterranean
  • Flowering Time: 9 weeks
  • Yields: 450-500 g/m²
  • Flavors: Spicy, Earthy, Fruity, Woody, Pepper, Lemon, Pine
  • Effects: Happy, Creative, Euphoric, Energetic, Uplifted
  • Medical Benefits: Stress, Stress-induced headaches, Lack of energy, Mood swings, Pains, Aches

Users commonly designate Jack Herer as the “perfect blend” of Indica and Sativa! The hybrid got its name after the legendary cannabis activist Jack Herer. It is exclusively created to provide happy feelings with lots of benefits in many medical conditions.

Jack Herer can be grown indoors and outdoors, and both methods can get you similar yields per plant. If you’re striving to get a clear-headed high and just want to feel amusing, Jack Herer is your go-to strain.

Not to mention its long list of therapeutic usage (in the above chart), Jack Herer is also rich in flavor profile, lingering your palate with fresh soil, pine, citrus, and woody hints.

Get Jack Herer at the lowest price

#9 – Sour Diesel | Most Popular Hybrid in the World

Sour Diesel - best hybrid strains

Sour Diesel Strain Information 🌱

  • Seedbank: Crop King Seeds
  • Variety: 60% Sativa + 40% Indica
  • Sex: Feminized
  • Genetics: Sour Diesel x DNL (believed)
  • THC: 18.50%
  • CBD: 0.8%
  • Growing Difficulty: Moderate
  • Climate: Indoor, Outdoors
  • Flowering Time: 8-10 weeks
  • Yields: 300-400 g/m²
  • Flavors: Pungent fuel, Citrus, Fresh soil 
  • Effects: Fast acting, Cerebral high, Uplifting, Couch lock
  • Medical Benefits: Stress, Depression, Chronic fatigue, Pain, Anxiety

As titled, Sour Diesel is by far the most popular hybrid strain in the cannabis universe. The diesel-like aroma is so intense that this weed got its name for having this trait. Stunning potency, quick effects, and great yields remain the prime factors behind this fabulous strain.

The flowers of Sour Diesel might take 10 weeks to mature, but the reward you get afterward is second to none. What users love about Sour D is the unique smell of fuel that tantalizes everyone. Give it a try.

This legend pumps up your dopamine instantly. The physical energy will be followed by the cerebral effects. With 18.5% THC, each puff will rev up your senses just like that! The strain has been enjoying the fame for many decades, and it doesn’t seem to fade away anytime soon.

Get Sour Diesel at the lowest price

#10 – Gold Leaf | High-yielding Hybrid from the Expert

Gold Leaf strain

Gold Leaf Strain Information 🌱

  • Seedbank: ILGM
  • Variety: 60% Indica + 40% Sativa
  • Sex: Feminized
  • Genetics: Not specified
  • THC: Up to 21%
  • CBD: Low
  • Growing Difficulty: Moderate
  • Climate: Indoors, Mediterranean, Continental, Steppe
  • Flowering Time: 9 weeks
  • Yields: 450-650 g/m²
  • Flavors: Herbal, Sweet, Earthy, Spicy, Pungent
  • Effects: Euphoric, Uplifted, Relaxed, Happy
  • Medical Benefits: Stress, Lack of Appetite, Fatigue

This hybrid comes straight from the expert himself. After years of expertise, Robert Bergman, the founder of ILGM, developed this beauty to entice us with its stunning effects and high yields.

I ordered this variety a few times, and every time I get stunned to see the results of my hard work. The high-quality Gold Leaf seeds grow amazingly well to turn into tall and healthy plants with swollen, long colas and flowers with golden-yellow trichomes. 

I am definitely going to repurchase Gold Leaf!

As you start toking your pot, the euphoric-driven high will blaze up your mood with a touch of giggly and creativity. All in all, the fusion of unique pungent aroma, tantalizing flavors, medical usage, and mood-lifting effects make this strain worth a try.

Get Gold Leaf at the lowest price

What are the medical benefits of hybrid marijuana strains?

You will find a range of Sativa-dominant, Indica-dominant, and evenly balanced hybrid weed from many dispensaries. If you crave to try a strain that keeps your physical energy intact and renders clear-headed relaxation, there’s always a perfect hybrid for you.

Hybrid buds can also relieve undesired effects of many ailments. Many researchers have revealed that cannabis-derived treatments can, in fact, be the next big thing in medical marijuana application and can replace traditional drugs in many conditions.

Many studies indicate that cannabis may help treat neuropathic pain, loss of appetite, seizuresautism, muscle cramps, migrainecancer-related pain, and many more. 

Not only do they vary in effects, but many hybrid strains also carry unique cannabinoids like CGB and THCV that are also beneficial in treating various inflammatory diseases. It’s worth analyzing a range of hybrid marijuana to realize which one heals which condition effectively.

Some hybrid weed strains are more potent than others, while some flash eye-catching beauty and deliver mouthwatering flavors

The world of hybrids is just endless!

Last Words

While Indica and Sativa remain naturally-grown cannabis, some classic weeds have become immensely popular hybrid strains among recreational users, medical patients, enthusiastic growers, and marijuana strain genetics researchers.

Along with medical benefits, planting the best hybrid marijuana strains is highly recommended to get diversity in flavonoids, fragrances, effects, and most of all, your fun growing experience.

No matter if you’re a hardcore fan of pure Sativa or Indica strains, why don’t you enjoy the best of both worlds in one strain?

Wishing you a healthy hybrid pot planting!


What’s better: Sativa, Indica, or Hybrid?

Sativa strains are energetic, causing mind-high, and mostly have citrus flavonoids. Indica strains are sedating, inducing body-high, and mostly exhibit earthy and skunky terpenes. While hybrids have various degrees of Sativa and Indica, if you want to enjoy a balanced fusion of effects and flavors, hybrid strains are better.

What is the most popular hybrid strain

Gorilla Glue is the most popular and potent hybrid strain with a perfectly balanced proportion (50/50) of Sativa and Indica genetics.

What are the side effects of hybrid strains?

Mild dry eyes and cottonmouth are usual side effects. But if you consume a potent hybrid in a higher dose, it could provoke slight paranoia.

What is a hybrid cannabis strain?

Hybrids combine indica and sativa genetics. Indicas, renowned for their physical effects, and sativas, known for their mental effects, can be mixed to create a strain that gives both physical and intellectual effects. Hybrid strains might be both upper and downer depending on the dominant species.

What are the strongest hybrid strains?

The strongest hybrid strains are OG Kush, Wedding Cake, Blissful Wizard, Girl Scout Cookies, and White Widow.

What is the most balanced hybrid strain?

While hybrid refers to combining Indica and Sativa strains, a balanced strain refers to your cannabis’s THC and CBD components being equally available.
Best Balanced hybrid strains include Cannatonic and Chiquita Banana.

Why are hybrid strains the best?

Hybrids are gaining popularity due to their rich flavours, enticing aroma, and health benefits. However, all hybrid marijuana strains are not created equal. Each hybrid has unique properties, aroma, and smoking experience.

What are the best sativa dominant hybrid strains?

Green Crack, Blue Dream, Strawberry Cough, Sour Diesel, Super Silver Haze are some of the best sativa dominant hybrid strains.

What is an indica dominant hybrid?

An indica-dominant marijuana strain is most likely a cross (hybrid) of indica and sativa cannabis strains; however, it leans more toward the indica side in terms of growth pattern and effects on the end-user. Indica dominant strains are excellent for pain relief.

Is Hybrid an upper or downer?

Hybrid strains might be both higher and lower depending on the dominant species. The effects of an Indica vs. Sativa high, for example, differ.
Because of the greater quantities of THC and low levels of CBD, sativa strains have an upper, euphoric “head high” that generates an energetic impact and boosts creativity. Indica is noted for providing a “body high” rather than a “head high.” It is commonly used for relaxing, hunger stimulation, sleep help, and pain treatment.

What effect does a hybrid gummy (sativa/indica) have?

The effects of a hybrid strain can include traits from both sativa and indica strains, which makes sense given that the hybrid is derived from both.
Sativa is commonly connected with effects such as a “mind high” or an energetic, anxiety-reducing impact.
Indica strains are frequently suggested for use at night since many patients find them beneficial for sleeping.

What are the effects of a sativa hybrid strain?

Sativa frequently induces a “mind high” or an energetic, anxiety-relieving effect. You may feel active and creative if you utilise sativa-dominant strains rather than relaxed and sluggish. Sativa can be used throughout the day or at night because of its energising effect.

What is the best 50-50 hybrid strains?

Chiquita Banana is a well-balanced hybrid cannabis strain with a 50:50 Indica to Sativa ratio created by crossing OG Kush and Banana.

1 thought on “Top 10 Best Hybrid Strains 2022 – Reviews & Buyer’s Guide”

Leave a Comment